Diane Boschelli : rechercher sur Z-Library

James B. Kramer, Diane H. Boschelli, David T. Connor

Année:

2009

Langue:

english

Fichier:

PDF, 318 KB

english, 2009

Synthesis of 2,6-di-tert-butylphenols linked to 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

Journal:

Journal of Heterocyclic Chemistry

Année:

1994

Fichier:

PDF, 439 KB

1994

Identification and optimization of indolo[2,3-c]quinoline inhibitors of IRAK4

Tumey, L. Nathan, Boschelli, Diane H., Bhagirath, Niala, Shim, Jaechul, Murphy, Elizabeth A., Goodwin, Deborah, Bennett, Eric M., Wang, Mengmeng, Lin, Lih-Ling, Press, Barry, Shen, Marina, Frisbie, Ri

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.40 MB

english, 2014

ChemInform Abstract: Inhibitors of Src Tyrosine Kinase: The Preparation and Structure—Activity Relationship of 4-Anilino-3-cyanoquinolines and 4-Anilinoquinazolines.

Yanong D. Wang, Karen Miller, Diane H. Boschelli, Fei Ye, Biqi Wu, M. Brawner Floyd, Dennis W. Powell, Allan Wissner, Jennifer M. Weber, Frank Boschelli

Journal:

Diane H. Boschelli, et al. et al.

Année:

2001

Fichier:

PDF, 33 KB

2001

ChemInform Abstract: Synthesis and Src Kinase Inhibitory Activity of a Series of 4-Phenylamino-3-quinolinecarbonitriles.

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 30 KB

english, 2001

Inhibition of Src Kinase Activity by 4-Anilino-7-thienyl-3-quinolinecarbonitriles.

Diane H. Boschelli, Daniel Y. Wang, Fei Ye, Ayako Yamashita, Nan Zhang, Dennis Powell, Jennifer Weber, Frank Boschelli

Journal:

Diane H. Boschelli, Fei Ye

Année:

2002

Fichier:

PDF, 34 KB

2002

Preparation of a Series of Benzothieno[3,2-b]pyridine-3-carbonitriles and Benzofuro[3,2-b]pyridine-3-carbonitriles.

Journal:

Diane H. Boschelli, Dennis Powell, Jennifer M. Golas, Frank Boschelli

Année:

2002

Langue:

english

Fichier:

PDF, 37 KB

english, 2002

Inhibition of Src Kinase Activity by 4-Anilino-5,10-dihydropyrimido[4,5-b]quinolines.

Journal:

Yanong D. Wang, Diane H. Boschelli, Steven Johnson, Erick Honores

Année:

2003

Fichier:

PDF, 117 KB

2003

A Facile One-Pot Synthesis of 2-Substituted-3-aminoquinolines: Preparation of Benzo[b]naphthyridine-3-carbonitriles.

Journal:

Ana Carolina Barrios Sosa, Diane H. Boschelli, Fei Ye, Jennifer M. Golas, Frank Boschelli

Année:

2004

Fichier:

PDF, 223 KB

2004

Synthesis and Inhibition of Src Kinase Activity by 7-Ethenyl and 7-Ethynyl-4-anilino-3-quinolinecarbonitriles.

Journal:

Ana Carolina Barrios Sosa, Diane H. Boschelli, Biqi Wu, Yan Wang, Jennifer M. Golas

Année:

2004

Fichier:

PDF, 76 KB

2004

Further Studies on Ethenyl and Ethynyl-4-phenylamino-3-quinolinecarbonitriles: Identification of a Subnanomolar Src Kinase Inhibitor.

Journal:

Diane H. Boschelli, Fei Ye

Année:

2005

Fichier:

PDF, 21 KB

2005

Preparation of a series of benzothieno[3,2-b]pyridine-3-carbonitriles and benzofuro[3,2-b]pyridine-3-carbonitriles

Journal:

Journal of Heterocyclic Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 74 KB

english, 2002

C-5 Substituted heteroaryl 3-pyridinecarbonitriles as PKCθ inhibitors: Part I

Joan Subrath, Daniel Wang, Biqi Wu, Chuansheng Niu, Diane H. Boschelli, Julie Lee, Xiaoke Yang, Agnes Brennan, Divya Chaudhary

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 290 KB

english, 2009

Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCθ inhibitors

Diane H. Boschelli, Joan Subrath, Chuansheng Niu, Biqi Wu, Yan Wang, Julie Lee, Agnes Brennan, Melisa Ho, Bijia Deng, Xiaoke Yang, Xin Xu, Louis Leung, Jianyao Wang, James Atherton, Divya Chaudhary

Journal:

Diane H. Boschelli, David T. Connor, Mark E. Lesch, Denis J. Schrier

Année:

2010

Langue:

english

Fichier:

PDF, 499 KB

english, 2010

Inhibition of adhesion molecule expression by N-alkylthiopyridine-benzo[b]thiophene-2-carboxamides

Journal:

Bioorganic & Medicinal Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 526 KB

english, 1996

Facile preparation of new 4-phenylamino-3-quinolinecarbonitrile Src kinase inhibitors via 7-fluoro intermediates: Identification of potent 7-amino analogs

Diane H. Boschelli, Biqi Wu, Fei Ye, Haris Durutlic, Jennifer M. Golas, Judy Lucas, Frank Boschelli

Journal:

Bioorganic & Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 172 KB

english, 2008

5-Vinyl-3-pyridinecarbonitrile inhibitors of PKCθ: Optimization of enzymatic and functional activity

L. Nathan Tumey, Niala Bhagirath, Agnes Brennan, Natasja Brooijmans, Julie Lee, Xiaoke Yang, Diane H. Boschelli

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2009

Investigation of the effect of varying the 4-anilino and 7-alkoxy groups of 3-quinolinecarbonitriles on the inhibition of Src kinase activity

Diane H. Boschelli, Fei Ye, Biqi Wu, Yanong D. Wang, Ana Carolina Barrios Sosa, Deanna Yaczko, Dennis Powell, Jennifer M. Golas, Judy Lucas, Frank Boschelli

Journal:

Ana Carolina Barrios Sosa, Diane H Boschelli, Fei Ye, Jennifer M Golas, Frank Boschelli

Année:

2003

Langue:

english

Fichier:

PDF, 177 KB

english, 2003

Synthesis and inhibition of Src kinase activity by 7-ethenyl and 7-ethynyl-4-anilino-3-quinolinecarbonitriles

Journal:

Diane H. Boschelli, Biqi Wu, Ana Carolina Barrios Sosa, Joan J. Chen, Jennifer M. Golas, Frank Boschelli

Année:

2004

Langue:

english

Fichier:

PDF, 257 KB

english, 2004

Inhibition of Src kinase activity by 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-heteroaryl-thieno[3,2-b]pyridine-6-carbonitriles

Journal:

Biqi Wu, Ana Carolina Barrios Sosa, Diane H. Boschelli, Frank Boschelli, Erick E. Honores, Jennifer M. Golas, Dennis W. Powell, Yanong D. Wang

Année:

2005

Langue:

english

Fichier:

PDF, 113 KB

english, 2005

7-(Aryl/heteroaryl-2-ylethynyl)-4-phenylamino-3-quinolinecarbonitriles as new Src kinase inhibitors: Addition of water solubilizing groups

Journal:

Diane H. Boschelli, Ana Carolina Barrios Sosa, Jennifer M. Golas, Frank Boschelli

Année:

2006

Langue:

english

Fichier:

PDF, 122 KB

english, 2006

Inhibition of Src kinase activity by 7-ethynyl-4-phenylamino-3-quinolinecarbonitriles: Identification of SKS-927

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 150 KB

english, 2007

Synthesis and PKCθ inhibitory activity of a series of 4-(indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitriles

Diane H. Boschelli, Biqi Wu, Ana Carolina Barrios Sosa, Joan Chen, Magda Asselin, Derek C. Cole, Julie Lee, Xiaoke Yang, Divya Chaudhary

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 131 KB

english, 2008

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Scott C. Mayer, Annette L. Banker, Frank Boschelli, Li Di, Mark Johnson, Cynthia Hess Kenny, Girija Krishnamurthy, Kristina Kutterer, Franklin Moy, Susan Petusky, Malini Ravi, Diane Tkach, Hwei-Ru Tso

Journal:

L. Nathan Tumey, Diane H. Boschelli, Julie Lee, Divya Chaudhary

Année:

2008

Langue:

english

Fichier:

PDF, 273 KB

english, 2008

2-Alkenylthieno[2,3-b]pyridine-5-carbonitriles: Potent and selective inhibitors of PKCθ

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 183 KB

english, 2008

Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Lori M. Miller, Scott C. Mayer, Dan M. Berger, Diane H. Boschelli, Frank Boschelli, Li Di, Xuemei Du, Minu Dutia, Middleton B. Floyd, Mark Johnson, Cynthia Hess Kenny, Girija Krishnamurthy, Franklin M

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 196 KB

english, 2009

Second generation 4-(4-methyl-1H-indol-5-ylamino)-2-phenylthieno[2,3-b]pyridine-5-carbonitrile PKCθ inhibitors

Biqi Wu, Diane H. Boschelli, Julie Lee, Xiaoke Yang, Divya Chaudhary

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 164 KB

english, 2009

Synthesis and PKCθ inhibitory activity of a series of 4-indolylamino-5-phenyl-3-pyridinecarbonitriles

Russell G. Dushin, Thomas Nittoli, Charles Ingalls, Diane H. Boschelli, Derek C. Cole, Allan Wissner, Julie Lee, Xiaoke Yang, Paul Morgan, Agnes Brennan, Divya Chaudhary

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 375 KB

english, 2009

4-Anilino-7-pyridyl-3-quinolinecarbonitriles as Src kinase inhibitors

Nan Zhang, Biqi Wu, Diane H. Boschelli, Jennifer M. Golas, Frank Boschelli

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 475 KB

english, 2009

First generation 5-vinyl-3-pyridinecarbonitrile PKCθ inhibitors

Chuansheng Niu, Diane H. Boschelli, L. Nathan Tumey, Niala Bhagirath, Joan Subrath, Jaechul Shim, Yan Wang, Biqi Wu, Clark Eid, Julie Lee, Xiaoke Yang, Agnes Brennan, Divya Chaudhary

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 535 KB

english, 2009

Synthesis and PKCθ inhibitory activity of a series of 5-vinyl phenyl sulfonamide-3-pyridinecarbonitriles

Jaechul Shim, Clark Eid, Julie Lee, Erica Liu, Divya Chaudhary, Diane H. Boschelli

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 246 KB

english, 2009

Optimization of 7-alkene-3-quinolinecarbonitriles as Src kinase inhibitors

Diane H. Boschelli, Daniel Wang, Yan Wang, Biqi Wu, Erick E. Honores, Ana Carolina Barrios Sosa, Inder Chaudhary, Jennifer Golas, Judy Lucas, Frank Boschelli

Journal:

Yanong D Wang, Diane H Boschelli, Steven Johnson, Erick Honores

Année:

2010

Langue:

english

Fichier:

PDF, 501 KB

english, 2010

A facile one-pot synthesis of 2-substituted-3-aminoquinolines: preparation of benzo[b]naphthyridine-3-carbonitriles

Journal:

Tetrahedron

Année:

2004

Langue:

english

Fichier:

PDF, 296 KB

english, 2004

Enantioselective synthesis of (+)-kjellmanianone

Bang-Chi Chen, Michael C. Weismiller, Franklin A. Davis, Diane Boschelli, James R. Empfield, Amos B. Smith III

Journal:

Tetrahedron

Année:

1991

Langue:

english

Fichier:

PDF, 870 KB

english, 1991

Synthesis of amphotericin B. 2. fragment C-D of the aglycone

Diane Boschelli, Toshiro Takemasa, Yasuhiro Nishitani, Satoru Masamune

Journal:

Diane Harris Boschelli, Dennis Powell, Veronica Sharky, M.F. Semmelhack

Année:

1985

Langue:

english

Fichier:

PDF, 257 KB

english, 1985

An improved synthesis of glycinamide ribonucleotide

Journal:

Diane Boschelli, Amos B. Smith III

Année:

1989

Langue:

english

Fichier:

PDF, 132 KB

english, 1989

Total synthesis of (±)-xanthocidin and (±)-desdihydroxy-4,5-dihydroxanthocidin

Journal:

Diane Boschelli, Amos B. Smith III, Orum D. Stringer, Robert H. Jenkins Jr., Franklin A. Davis

Année:

1981

Langue:

english

Fichier:

PDF, 247 KB

english, 1981

An asymmetric synthesis of (+)-kjellmanianone

Journal:

Diane Boschelli, John W. Ellingboe, Satoru Masamune

Année:

1981

Langue:

english

Fichier:

PDF, 265 KB

english, 1981

Aldol methodology: synthesis of syn-3-hydroxy-2-vinylcarbonyl compounds

Journal:

Année:

1984

Langue:

english

Fichier:

PDF, 230 KB

english, 1984

Inhibitors of Src tyrosine kinase: the preparation and structure–activity relationship of 4-anilino-3-cyanoquinolines and 4-anilinoquinazolines

Yanong D. Wang, Karen Miller, Diane H. Boschelli, Fei Ye, Biqi Wu, M.Brawner Floyd, Dennis W. Powell, Allan Wissner, Jennifer M. Weber, Frank Boschelli

Journal:

Diane H. Boschelli, David T. Connor, Paul J. Kuipers, Clifford D. Wright

Année:

2000

Langue:

english

Fichier:

PDF, 136 KB

english, 2000

Synthesis and cyclooxygenase and 5-lipoxygenase inhibitory activity of some thiazolidene-4-one analogs of meclofenamic acid

Journal:

James B. Kramer, Diane H. Boschelli, David T. Connor, Catherine R. Kostlan, Daniel L. Flynn, Richard D. Dyer, Dirk A. Bornemeier, John A. Kennedy, Clifford D. Wright, Paul J. Kuipers

Année:

1992

Langue:

english

Fichier:

PDF, 222 KB

english, 1992

Synthesis of reversed hydroxamic acids of indomethacin: dual inhibitors of cyclooxygenase and 5-lipoxygenase

Journal:

Diane H. Boschelli, David T. Connor, Milton Hoefle, Dirk A. Bornemeier, Richard D. Dyer

Année:

1992

Langue:

english

Fichier:

PDF, 364 KB

english, 1992

Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase

Journal:

James B. Kramer, Diane H. Boschelli, David T. Connor, Catherine R. Kostlan, Paul J. Kuipers, John A. Kennedy, Clifford D. Wright, Dirk A. Bornemeier, Richard D. Dyer

Année:

1992

Langue:

english

Fichier:

PDF, 227 KB

english, 1992

Cyclooxygenase and 5-lipoxygenase inhibitory activity of 2,6 di-t-butylphenols linked by a sulfur atom to 1,3,4-thiadiazoles and 1,3,4-oxadiazoles

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 240 KB

english, 1993

Inhibition of Src kinase activity by 4-anilino-7-thienyl-3-quinolinecarbonitriles

Diane H. Boschelli, Daniel Y. Wang, Fei Ye, Ayako Yamashita, Nan Zhang, Dennis Powell, Jennifer Weber, Frank Boschelli

Journal:

Diane H. Boschelli, Dennis Powell, Jennifer M. Golas, Frank Boschelli

Année:

2002

Langue:

english

Fichier:

PDF, 133 KB

english, 2002

Inhibition of Src kinase activity by 4-anilino-5,10-dihydro-pyrimido[4,5-b]quinolines

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 172 KB

english, 2003

Synthesis and evaluation of 4-Anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade

Dan Berger, Minu Dutia, Dennis Powell, Biqi Wu, Allan Wissner, Diane H. Boschelli, M.Brawner Floyd, Nan Zhang, Nancy Torres, Jeremy Levin, Xuemei Du, Donald Wojciechowicz, Carolyn Discafani, Constance

Journal:

Bruce H. Toder, Diane Boschelli, Amos B. Smith

Année:

2003

Langue:

english

Fichier:

PDF, 173 KB

english, 2003

Crystal and molecular structure of geiparvarin

Journal:

Journal of Chemical Crystallography

Année:

1979

Langue:

english

Fichier:

PDF, 437 KB

english, 1979

A cell-based screen for inhibitors of protein folding and degradation

Frank Boschelli, Jennifer M. Golas, Roseann Petersen, Vincent Lau, Lei Chen, Diane Tkach, Qiang Zhao, Dave S. Fruhling, Hao Liu, Chaneun Nam, Kim T. Arndt

Journal:

Cell Stress and Chaperones

Année:

2010

Langue:

english

Fichier:

PDF, 518 KB

english, 2010

Total synthesis of (±)-desepoxy-4,5-didehybromethylenomycin A

Diane Boschelli, Robert M. Scarborough Jr., Amos B. Smith III

Journal: